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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72f1d18322c8aec271100cc6fd2f3a87815112fc8b97ff3e9bac04f08a0c26e' 
  AND token = 'ePKrf5WjgFiGAtI2JmXds7pWMvfsXy55ZXsVI4Rf5q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}