SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26201319e8ea7f2595c0fbfabb9e214b1923e918b74edbb011604dcf2c731f75' 
  AND token = '7xfw2vEMJXg6JB6XG+fxzWb6iEHC0dJmGhntTCoyeV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}