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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2858e4d34974576d9f0e5e9905b7c37eccfe3d488058efd062cc2d173acecba3' 
  AND token = 'REH+0d4MRnfFa5nRD75YcEGwZtktH6ZKxJ2oVeh88JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}