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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e7a87bac2a798350c30a5b1360708a10d2fb3757aea6421c21543311879052' 
  AND token = 'DUJwpLNWwFasQxgv2mdvKFYGCaGHp1NMphWnQ+7Qaq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}