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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8680ab3a7f5cef18ed7a5fe6286224b94a3cdc5a748490f794b03ab34314bcc0' 
  AND token = 'gcNRZJdm3TI+mP9pk6WWmBXctO6itF5gFRtPhev+bC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}