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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c34da66fa8301073a3a1167ccc10a0c5bf57f300302b05b64daf0f0fc65f8a61' 
  AND token = 'Pn/1Roh/IQNJHqcT5CHKjyEX+++Fl/zD5v7WjpCmnG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}