SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d8057a386a7de10d659d94a6687314fef349ace50ca025fcd219f782bfea26' 
  AND token = 'TmyZymzT+ZEuor2B8KOm8kvU7aM/tWrCh+j6UUM7hZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}