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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd98b1c14b6a1b64a19cb2c518e2875da8d5d5dd492b8a21b888176ef54527373' 
  AND token = 'qH+IF0qnoXRQxabbnJHxdDCB7xp7EnmlJ6jgsGobSwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}