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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acb24bc031534c9cc349fde5fb7ce6c0714ac84ce1f285f5375e05987c44ecb' 
  AND token = 'eFVGxseSXmNZRLSklgjej5+azzZV7AMOW/GQ/mZbv1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}