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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22167b93d7567d00ae4ce2aa8dc80699dfd4f9c17052eebd4c2fcc8fed10e14e' 
  AND token = 'itA5hxEsef+Qehq7lfyqCPtFeNvHml1nCdChV1HslN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}