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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5f16a3b7dac26ff54bfe62d0cc13c2818e36483630c9ee9c8d6d28efe39bc0' 
  AND token = 'I490vT//3v00E2xpCpCBnmKwQwW5MDNycxpMFBgH65E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}