SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0045e0fafe619d790dd1b08adaa733207048839caa0e4ade1bf7dc7e6d101826' 
  AND token = 'TFP+HGkUJ8m794u5zDVcO7EiQIjomR1BHcuNXjXG8Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}