SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af41a8c3ae81123002090e278f8cfc5e006f6b9e8a76b99abe1bf642f0aac5a' 
  AND token = 'OQzx9HeV5+hws47oN6IIdvVu61wyzu1gVMj0cxgdh2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}