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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c15329ddb6af7e94e16b05c3dd1afcdb3a3452692c64fdf3042ede2b5d6d243' 
  AND token = 'hsCnKG1Ld74ivbOujq0SiqUan339YlFG4Yr9UvUj4/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}