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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '401228c4492e3eb19de24cfbd118058c6cdf2074948f262f4d9ec3206f8c8505' 
  AND token = '0TRP522jMGaaHpyJmcUrTS9cRsHZNupYzF2b0zMsXTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}