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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42877110889c1c84a76cebf4c85e4f7a9087fe9e6775a1861f172c18d381fa4e' 
  AND token = 'Ais8+llf4Jm/TZSGj+Q9n+/nDPSpT0GRfIxdTyX+mxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}