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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90d27c43ae3c233d08dc1193b95fae9c68781d3150c1a884d14c4c498ce44820' 
  AND token = '3Ubmo/QZRU7n2ZprHPGYqt6VTAbzB05WKVoyeDJY4s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}