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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154ec5f630b42d3e5b20a3a6bc6b2eb0dfd258a5f7530b9fcc6fb2f6908408e8' 
  AND token = 'D0cjeBywFlyz0iUEhLQxKL83PRC4hyYwEJXuXZQCm6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}