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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6790224a0062e8c3fc8c5dfb1d7c79ed3ba18ddffb64fb579a711633dad48cd6' 
  AND token = 'zVPn0c1rwgO7WtAz9CKlcOe7bw/p0uwU8maVgzTS1wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}