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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1751068779bf94edfa751823eaf66ba310a78e0e9c94f746f1575dad1cc00d53' 
  AND token = '5hH3FfVnjWCaQSUe2u8O+5wI38A+9qwe+4vMod2tegQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}