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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ddbe5000fd59aa6f080d0754103c1268d9aa120ad3906fcccd0bab3fd12546' 
  AND token = '00h4bUCQG2q/5rgS64rxvvlOK93SFrmCgY8bl/uZDCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}