SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ee442788587cc16b2a2db3960dee2483b524f343ed2327e2a3197d2e4c21f3' 
  AND token = 'w5+K5P4PWQq+AVzYIs/kcpCKB04egfA9NW1zh3ThykA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}