SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f80bbd0dbfb3f407c57b354c8dbda37f3f40efe836169c346f48a6f14e04d4' 
  AND token = 'xnGHcqpMTlVgO5dQ4vsDyUXOtIvrJDHWKPyzUD5W6Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}