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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6d8dc0e3770854479688c5ebed821a809aa8fecf5e169225a0bb8ef6625005' 
  AND token = 'S1GnEjxR31Ho8kii+Uyt4JfcwathMflqzAtNnMlDoyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}