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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cfe6f5b0788f9f18d37b742ad9de86c1feab24e214100959516b69a3bb40bf1' 
  AND token = 'JPm1E05reVMRpdTHmopwqKJ8dmawZPeJT6/jLzG4iIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}