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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '269c6c3161c754dc963551d9195885e5c3234b2ca0a29224fb43792d598e5b8e' 
  AND token = '0RO6TBDL3bSsd1uV/57NCOsoTw4dZEe3hlitV2QfVnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}