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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acccf9cd3e5b71cbe7eb2042f444b1ffb7c859544def203e8f983f78dc9c1e7b' 
  AND token = 'GRqcsorZDFEowaM50j55HsBLJvMd21e7aW3zwbBY6U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}