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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d249f11a719a9105896dd2b6480a7c90612760fbc0763c6bd62820a366d8d78' 
  AND token = 'bv2msm8kGRw8yoXkDKjTm0mKtBv5N7PG+4RFuNmm65o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}