SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d45297545a5ad9d65a2b6b341b42179afeb1c6f8f615068c6bfb56ee9a5bbab' 
  AND token = 'xVLw3i0fRb00aqg+wrQRWi6QBMod08Cei4rJkq74jG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}