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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a7649e966decf8ec9188ab14dc26695454a2484bc1c5215ecc6194218b42778' 
  AND token = '/Ajq/tujzhM9DPTDMvfq2VEu1/wHVwj1JrIj/5Hfd9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}