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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a92f424feac43cdf7e5e0f881bd03a62557e6ab6d425d168ab69376046390d01' 
  AND token = 'wFDjIi5uinASmLzvF+uiUFM053ld8v6XffIu9BOK8GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}