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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ffdb65913fe0e77c3845fae77a02941eab1d198a50ed49816dd5a737286723' 
  AND token = 'xlQeWENmavPMAbNgp7m9eYYcamKGpQxagnw37d+4ieY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}