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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d9626afd6592639d3071e3fe7290f3506d4740189325dc799408cd94a2e6c8d' 
  AND token = 'fC+cE3ZQNBQ65mKl/k6/oq/sXV7cF4fbuU95EBLw/70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}