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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9ebc27aa649ae4b6fab4b9c5c5d542b3ca234778161fe2f578d9869cf245d6b' 
  AND token = 'S5b9ZkbZwAZRdR9sx0UWM4sUT5RzpGLYM1XU5nA5sds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}