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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44807886730ba0f118955458cc10f94c55c02a00aea3c67522a30b1d4db337e4' 
  AND token = 'KfGwCwyt8yXilMpfcbo3gCemCe0EjO8KTfzzBleAab4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}