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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6c6576206d0c984388079a3c24f89fb497fda64ee492508ee5ba3641fd7559' 
  AND token = 'B62bxd1GGXuQfZ+/4xx5mK0pve0Jzi5DdJXx1nI2TXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}