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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26bf725ca7e0e1290a3dc22940de74a99b2d7b3705f209cf2e79b4a82029caa4' 
  AND token = 'AL1WSTGUy1yR4w1H9a5GaVF0XdhmGzKOzBs8PAVi60Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}