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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fb334852f76952dfbd4987a10d45c939490ea7c4ce4a9e0dbd7d75386c7350' 
  AND token = 'WTJ+In1qR4/L0SxYvLWUAwTRbemRL47NXKEdFXaYWDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}