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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9d10acbf4a0a9fe6488d65457299fcd7b195da7c927d6610b62690efd14f310' 
  AND token = 'Cz9Ruqg15kf1IMcmFHCEgFnrCHGqE8TE4RsphM8NTmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}