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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c46e56afcba3626691f08440b66027aa1f7ca4800eea245f3f17bcc662ce05b' 
  AND token = '2B/lFISlg4smL8AaUfafPCa/3G8uDoQpTsSDcvHK5FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}