SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae6a2c0a51105d3a919a50f972918e9b366128cccef3fb876df9e98a46aca766' 
  AND token = '/AV9A44uWXyy27Ey1senjLA9ec4t+1MGa+gINsqe16k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}