SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defa39117ae18e7b98717ee3d914015177d6601eaba6af054fb1560bd217df94' 
  AND token = 'AycsY+1P+ONrXycqy8QRQ8dBIFAX3lcj1YHjVcVYyrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}