SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87dd88c218fd52c8a6d1da573226bccb1dffa3d48836b4e837e46a773cf2e083' 
  AND token = 'wR9fK9zQmeQ2CEK1N1PgpOsQZmBkXQwQKPkWRai4y78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}