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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78b2d0e45f187067577bfd5e80d494c1078837e4021af5404f72305c4f6647d' 
  AND token = 'yPXztJneneNH0AucPd3PY5QVwRlAEn8q6zCPuyI2w5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}