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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b644b01e5b72184fc3a19fc4f1c1d47f362399200cf487523b1e4d7041be0dcf' 
  AND token = 'IlnueFRrCwILH1g3EUzcCxXSnela01st4gBYJmH0y7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}