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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f9e81b49425853183ed1ad939633d016a4c7a631cf9d846c8962df5717d98b' 
  AND token = 'WXG1gZMuelDoOpxSS3DncUJcRr33xjNK/sdc+/5UxK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}