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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb1244b64b3e9cc27f06ec64a33b55f64648705346855b6e7d679b9e9cca1b0' 
  AND token = 'tc+cstQIII6IAROYpA52d482PTukC7d632PxXTDy9dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}