SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8516c72557d02df0a58a428de18faea35103ec5ca4dee332a6db25e2c10d93f8' 
  AND token = 'GYghrkwnCLtw5UK2mOhXk75O94rQGU2kSovo1UbYggk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}