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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8ab78c1753c290a771d483753236f5d6a83d3aba5edb39f52a9dc392e5c82b' 
  AND token = 'gFxTf/j6mhsVe0TS6cnuzWOEcCnBJ7+B899C1fiCA98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}