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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69657d39fa4ab200aeadaf04e6e393e54c207fbb6e150816c30e0e471c151354' 
  AND token = '7YFOyaAZeaM+BL0eM9p7IkRqivRMaAhQmLj82FF4s8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}